01 - If the chicken breasts are thick, place them between sheets of plastic wrap and gently pound with a meat mallet to an even ½-inch thickness for uniform cooking.
02 - In a large mixing bowl, whisk together the buttermilk, egg, kosher salt, black pepper, garlic powder, and paprika until fully combined.
03 - Submerge the chicken breasts in the marinade, cover the bowl, and refrigerate for at least 30 minutes or up to 4 hours for deeper flavor penetration.
04 - In a shallow dish, combine the all-purpose flour, panko breadcrumbs, kosher salt, smoked paprika, and cayenne pepper. Mix thoroughly to distribute the seasonings evenly.
05 - Remove each chicken breast from the marinade, letting excess drip off, and dredge firmly in the flour-breadcrumb mixture. Press gently on all sides to ensure an even, adherent coating.
06 - Pour vegetable oil into a large skillet or deep frying pan to a depth of about ½ inch. Heat over medium-high heat until the oil shimmers and reaches 350°F.
07 - Carefully place the coated chicken breasts in the hot oil and fry for 5 to 7 minutes per side until deeply golden brown and crispy. The internal temperature should reach 165°F when checked with a meat thermometer.
08 - Transfer the fried chicken to a paper towel-lined plate to drain excess oil. Allow the chicken to rest for 2 to 3 minutes before slicing and serving.